chronic granulomatous disease, case report and review of literature

نویسندگان

mitra mehrazma

khadije mahlouji

reza taghipour

چکیده

chronic granulomatous disease (cgd) is a rare inherited disorder characterized by inability of phagocytes to generate oxygen radicals needed for intracellular killing of phagocytic microorganisms. we report a 2.5-year-old iranian female with multiple liver abscesses. she was admitted in surgical ward because of abdominal pain and fever for one month duration that had no response to conventional antibiotic treatment. the results of laboratory tests were: wbc=17000, neutrophils=82%, lymph=17%, esr=100. other tests except nitroblue tetrazolium (nbt) and dihydrorhodamine (dhr) tests were negative and according to these two tests the final diagnosis was cgd. supportive care along with recombinant interferon γ and oral trimethoprim-sulfamethoxazole for prophylaxis of infections started. now after 18 months she is alive and healthy. any patient with recurrent or unusual lymphadenitis, hepatic abscesses, osteomyelitis at multiple sites, a family history of recurrent infections, or unusual infections with catalase positive organisms, like s. aureus, requires evaluation for cgd.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Chronic Granulomatous Disease, Case Report and Review of Literature

  Chronic granulomatous disease (CGD) is a rare inherited disorder characterized by inability of phagocytes to generate oxygen radicals needed for intracellular killing of phagocytic microorganisms. We report a 2.5-year-old Iranian female with multiple liver abscesses. She was admitted in surgical ward because of abdominal pain and fever for one month duration that had no response to conventio...

متن کامل

Chromobacterium violaceum infection in chronic granulomatous disease: a case report and review of the literature

Introduction.Chromobacterium violaceum is an opportunistic human pathogen, associated with significant mortality, and has been reported in patients with chronic granulomatous disease (CGD), a genetic condition causing impaired phagocytosis. Case presentation. A 28-year-old man with a history of CGD presented with fever, pharyngitis, cervical lymphadenopathy and internal jugular vein thrombosis,...

متن کامل

Hip Joint Trevor Disease: Literature Review and a Case Report

Trevor disease or dysplasia epiphysealis hemimelica (DEH) is an extremely rare condition with incidence of about 1:1,000,000. Male to female ratio of reporting case is 3:1, and usually diagnosed between two and eight years old. It usually affects the medial portion of the joint, but lateral involvement is not uncommon. Hip-joint was affected in less than 4% of existing cases in the literature. ...

متن کامل

Rosai-Dorfman Disease: A Case Report and Literature Review

Rosai-Dorfman disease or sinus histiocytosis with massive lymphadenopathy is a rare disorder that typically manifests as lymphadenopathy and systemic symptoms whose etiology remains poorly elucidated. The diagnosis is based on immunohistochemistry. Its treatment is poorly defined but the prognosis is usually favorable. Here we report a 14 year old boy who presented with massive bilateral cervi...

متن کامل

Primary granulomatous hypophysitis: a case report and literature review.

Primary granulomatous hypophysitis (PGH) is a rarely occurred inflammatory disease of unknown etiology. We retrospective review a case of PGH treated by microsurgical transsphenoidal approach and review the appropriately documented cases of PGH collected from the literatures. The patient was a 56-year-old female who presented with 4 months history of headache and 2 months history of polyuria an...

متن کامل

Isolated Primary Hydatid Disease of Omentum; Report of a Case and Review of the Literature

Hydatid disease, most commonly caused by the larval stage of Echinococcus granulosus, affects mainly human liver and lung, and rarely other parts of the body. It is prevalent in most sheep-raising Mediterranean Countries including Iran. Peritoneal hydatid cyst, either primary or secondary, represents an uncommon but significant manifestation of the disease. The present case report describes a c...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of pathology

ناشر: iranian society of pathology

ISSN 1735-5303

دوره 4

شماره 2 2009

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023